From the name's point of view, Snail and Slug family genes are very easy to associate with a static, slow-moving biological process. But in fact, these genes can help guide dynamic, rapid early embryonic development when cells differentiate, migrate to various parts of the body, and differentiate into millions or even billions of specialized cells that make up the mature organism.
The Snail family genes are found in vertebrates and have corresponding genes in invertebrate cases such as Drosophila. For biologists, this means that these genes have very good interspecies conservation. It is reasonable to expect that the function of these genes will be the same in all vertebrates, including rats, frogs and birds.
In a study published in the latest issue of the Proceedings of the National Academy of Sciences, two Jackson Laboratory scientists, Thomas Gridley and Dr. Steven Murray, confirmed that the Snail gene plays the same role in vertebrates. character of.
The Snail genes in mice and birds are all related to controlling the asymmetrical differences between the sides of the body. All vertebrate bodies develop symmetrically, but some of the viscera are asymmetrically distributed. For example, the mammalian heart is on the left side of the body and the liver is on the right side.
In addition, Gridley and Murray also found that in the embryos of frogs and birds, the Snail gene family is required for formation and stratification of the corona cells of the nervous system.
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