Estrogen-producing enzymes in the brain are closely related to personality temperament
January 29, 2019 Source: Science and Technology Daily Author: Chen Chao
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];A team of the Japanese Institute of Physical Chemistry analyzed brain images by positron emission tomography (PET). The expression level of estrogen-producing enzyme, aromatase, in the brain was associated with personality.
The research team selected 11 healthy males and 10 females to determine the specific binding compound "Cetrozole" of aromatase by PET, to calculate the distribution and content of aromatase, and to use the test paper to personalize the aggressiveness and coordination of personality temperament. Determination. The results showed that the higher the aromatase content in the female amygdala, the stronger the aggression; the higher the aromatase content in the thalamus, the lower the coordination, regardless of gender. This suggests that human personality is associated with the amount of aromatase in the brain.
The aromatase that converts male hormones into female hormones is found in various parts of the body. The male hormone transmitted through the bloodstream can produce female hormones locally through the aromatase. From experiments in mice that lost the aromatase gene, aromatase was found to be associated with aggressive behavior and depressive behavior. Autopsy results on the human body also found that aromatase in the brain is associated with autism. However, so far, the association between human character, temperament and aromatase in the brain has been studied in volunteers.
PET is a method for quantitative visualization of molecular behavior in living organisms. The team developed a new PET probe that alters the inhibitors that bind to the aromatase and confirms the analysis of aromatase in the brain.
The results of this study provide clues for understanding human temperament and personality differences, and have positive implications for understanding the autism spectrum mechanism and improving symptoms.
The research results have recently been published in the British Science Report.
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