Release date: 2007-05-31
A retrospective study was conducted to evaluate the CT findings of abdominal lymph nodes in 52 patients with lymphoma, aiming to better understand the diagnostic value of CT imaging in identifying lymphadenopathy associated with lymphoma. The study included 16 patients with Hodgkin’s disease (HD) and 36 patients with non-Hodgkin’s lymphoma (NHL), all of whom had undergone surgery or biopsy for confirmation. The CT scans revealed distinct patterns of lymph node involvement. Among the cases, 10 patients showed a "mass-like" appearance—three with single, round, uniformly dense lymph nodes, and seven with multiple, fused lymph nodes forming separate masses. Another 34 patients exhibited a "lobular" pattern, characterized by multiple, round, swollen lymph nodes with clear margins and uniform density. Six patients presented with vascular invasion signs, such as embolization in the mesenteric, renal, or abdominal vessels, while two showed evidence of duodenal infiltration. Eight patients had a diffuse type, with characteristic "cobblestone" appearances on CT scans.
The CT findings varied significantly between HD and NHL. In 12 HD cases, the distribution, size, number, and fusion of lymph nodes differed from those seen in the 40 NHL cases. Additionally, 28 out of 52 patients had extranodal lymphoma, with the gastrointestinal tract being a common site. These patients often showed specific CT features that helped in their diagnosis. During follow-up, 15 patients displayed varying enhancement patterns—uniform, heterogeneous, or marginal. Twelve of them showed occasional calcifications along with reduced lesion size and number, and three patients experienced complete resolution of lesions after treatment.
This study highlights the importance of CT imaging in assessing abdominal lymph nodes in lymphoma patients. It not only helps in differentiating between various types of lymphomas but also plays a crucial role in monitoring treatment response and guiding further management. With its ability to detect characteristic imaging patterns, CT remains a valuable tool in the diagnostic and follow-up process of lymphatic diseases.
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