A team led by James Robl and Isao Ishida reported on a new technology that they developed in the course of a year of missing a cow that includes two versions of the gene. This is the first time that two versions of a gene have been removed in cattle in such a short time. The researchers removed such genes from the cultured bovine primary fibroblasts and then used this nucleus to culture cloned embryos. Through this technique, they cultivate cattle that lack antibodies to immunoglobulins, and cattle embryos lack protein prion proteins. This result broadens the technology that permanently removes some currently inactive genes. Whether the second result can make cattle no longer transmit prion disease - bovine spongiform encephalopathy?
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