Release date: 2010-09-07
It was learned from the University of Science and Technology of China that the Beijing Synchrotron Radiation Facility and the Hefei National Synchrotron Radiation Laboratory Joint Imaging Research Group led by the researcher Wu Ziyu have made major breakthroughs in the field of X-ray phase contrast imaging research, and their research results have overcome medical X-rays. The obstacles in the application of X-ray phase contrast imaging methods by CT technology lay the foundation for the formation of faster, more sensitive and safer X-ray phase CT technology. The research results were published in the recently published international authoritative journal, the Proceedings of the National Academy of Sciences, and were praised by reviewers as "a major breakthrough in X-ray imaging research in the past 20 years."
In the more than 100 years since the discovery of X-rays, traditional absorption-based X-ray imaging techniques have been widely used in many fields such as medical clinical diagnosis, biology, and safety inspection. However, its imaging technology is sensitive to heavy element-based objects (such as bones, metals, etc.), and can obtain clear images, while light soft elements are mainly biological soft tissues (such as early tumors, blood vessels) and polymer materials (such as Porous plastics, carbon fibers, high polymers) only give blurred images. In contrast, the newly developed X-ray phase contrast imaging in the past decade has obvious advantages, and can obtain high-definition (contrast) images of biological soft tissues composed of light elements. However, due to the cumbersome imaging method, the imaging time is too long, and the radiation dose is too high, it is not suitable for the imaging requirements of biomedical samples, and it is difficult to combine with medical X-ray CT technology.
The research team led by Wu Ziyu used the principle of X-ray frontal incidence and opposite incident absorption and the opposite angle of refraction to propose a research plan to overcome this problem. They have cooperated with the University of Tokyo and the X-ray imaging experts of Swiss Synchrotron Radiation Sources to carry out a series of experimental studies on soft tissues such as rat joints and brains, and obtained completely positive experimental results. The new method has the characteristics of simple, rapid, low radiation dose (at least 50% reduction of radiation dose), and can be combined with existing medical X-ray CT technology to form a new X-ray phase CT technique with simple operation and low radiation dose.
Source: Technology Daily
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